European Life Science Research Infrastructures
Catalogue of Services
What do LS RIs offer the life science community?
The 13 European Life Science Research Infrastructures (LS RIs) have the mission to support cutting-edge science by offering access to their resources and services to European scientists from academia and industry.
Resources and services can simply be consultation, access to experts, but also access to data and biological samples, use of data analysis tools, access to facilities (e.g. highly specialised microscopes) plus support from technicians and much more.
Some of these services are even free to use for institutions location in the RI's member states.
The Catalogue of Services, which has been developed within the CORBEL project, is the first tool to list the main services of all LS RIs at a glance and it aims to facilitate the utilisation of RI services by researchers from all over the world. The Catalogue of Services as displayed below aims to provide you a basic overview on existing services within distinct thematic fields.
You can either use the Catalogue of Services to identify a single RI to help you with your work or you can create a service pipeline, i.e. using several RIs simultaneously.
What’s your need?
Please select…
Samples
Data & Databases
Technologies & Facilities
- accreditated/certified facilities (ISO certified, GLP, GMP, GCP)
- adaptation / development of assays (compounds etc.)
- adaptation / development of assays (human/non-human samples)
- high-throughput screening
- imaging (biological)
- imaging (medical)
- isolation / cultivation / characterisation of microorganisms
- -omics technology platforms
- plant phenotyping technologies/facilities
- production of high quality protein samples
- structural biology technologies/software
Models & Tools
Expertise & Support
- biomarker validation
- biosecurity / biosafety (incl. regulatory) issues
- data management expertise
- development of project towards a medical application
- ethical / legal issues, informed consent
- innovation management support
- mouse model generation, phenotyping and cryopreservation
- multinational clinical trial (establishment / management / monitoring)
- outbreak / emergency response / epidemiology
- support to submit a project proposal
- systems biology expertise
- training courses
- The following RIs offer complementary services:
INFRAFRONTIER
Contact person(s): INFRAFRONTIER Scientific User Support
INFRAFRONTIER is the European research infrastructure for the development, phenotyping, archiving and distribution of model mammalian genomes. It is formed by more than 25 research centres in 14 European countries and Canada. In INFRAFRONTIER these partners join forces to commonly advance the basic understanding of human health and disease using mouse and rodent models.
Services provided
Services offered by INFRAFRONTIER include
- archiving and distribution of scientifically valuable mutant mouse strains
- rodent model development (mouse and rat) using gene targeting in embryonic ES-cells or CRISPR/CAS9 technologies
- systemic phenotyping of mutant mice for a whole-organism view on gene function
- germ-free (axenic) mice
- validated genetically engineered mouse models of cancer
- access to comprehensinve expertise and training
Costs
Some of the INFRAFRONTIER resources and services are provided free of charge, others entail user fees to recover costs.
There are periodic Open Calls to fund researchers, for detailed information see the INFRAFRONTIER website.
For further information please contact us.
Access modes
Access modalities vary with the kind of resource or service requested.
For further information please contact us.
Why work with us
INFRAFRONTIER provides access to unique resources and expertise to advance the understanding of human health and disease using mammalian models. Our users can rely on highest quality standards and long-standing experience. INFRAFRONTIER’s one-stop-shop facilitates efficient research.
Countries involved
DE, GR, FI, CZ, FR, EMBL
Services contact
Contact person(s): INFRAFRONTIER Scientific User Support
About
Europe urgently needs to find solutions for the grand challenges in the area of health. Different forms of cancer, metabolic diseases such as diabetes and obesity, chronic lung diseases, cardiovascular diseases, rare diseases, and infectious diseases are global threats to socio-economic well-being.
Mammalian models have proven to be a key resource for biomedical research to understand human diseases and to develop treatments for them. Mouse studies have been key to the six of the last 10 Nobel Awards in Medicine and Physiology and to breakthrough discoveries in the functional basis of human health and disease and are used in pre-clinical screening and drug development. The INFRAFRONTIER Research Infrastructure provides access to centralised high-quality resources and data for the development, phenotyping, archiving and distribution of mammalian models. Access is provided for individual researchers (bottom-up access) and for national, European and international research programmes (top-down access).
The INFRAFRONTIER Mouse Clinics offer access to a comprehensive first-line systemic phenotypic analysis covering a wide range of physiological functions ranging from cardiovascular, neuro-behaviour and metabolism expertise to detailed pathology assessments.
The nodes of the European Mouse Mutant Archive (EMMA) establish and manage a unified non-profit repository for maintaining medically relevant mouse mutants and making them available to the scientific community. EMMA is by far the largest mouse repository in Europe and the third-largest non-profit mouse archive worldwide. EMMA comprises over 5200 mutant mouse lines carrying targeted, transgenic, induced and other types of mutations.
INFRAFRONTIER also provides specialised services, training and consulting.
Please note: Most of the RIs are constantly developing their portfolio of services, so if you do not find the service/tool you are looking for, do not hesitate to contact the RI and ask for it!